Deflux

From WikiCover

Deflux from Q-Med is a viscous gel consisting of non-animal stabilized hyaluronic acid and dextranomer, a crosslinked polysaccharide that promotes the natural formation of connective tissue. Deflux is indicated for the treatment of children with VUR grades II - IV. The most frequent adverse event seen in clinical trials was urinary tract infections. Other adverse events reported -- ureteral dilatation, nausea, vomiting and abdominal pain -- occurred in approximately 1-3% of patients. Rare cases of postoperative dilatation of the upper urinary tract with or without hydronephrosis leading to temporary placement of a ureteric stent have been reported. Deflux is contraindicated in patients with non-functioning kidney(s), hutch diverticuli, ureterocele, active voiding dysfunction, or ongoing urinary tract infection. Since 1998, Deflux has been used in more than 40,000 children worldwide. Long-term follow up suggests that up to seventy percent of children treated with Deflux need no further treatment for VUR.

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Deflux reduced the incidence of recurrent urinary tract infections in children with VUR by sixty-two percent, according to a study published in the July 2007 issue of the Journal of Laparoendoscopic and Advanced Surgical Techniques.

Website: http://www.deflux.com/